Normal Limits

"Chance is the very guide of life"

"In practical medicine the facts are far too few for them to enter into the calculus of probabilities... in applied medicine we are always concerned with the individual" -- S. D. Poisson

November 15, 2005

Pediatrics - Do Pacifiers Reduce the Risk of Sudden Infant Death Syndrome? A Meta-analysis. (Hauck et al 2005)

A meta-analysis of 7 case-control studies looked at the association between SIDS and pacifier use.

Based on 4 studies that provided multivariate ORs controlling for a variety of factors including sleeping position, usual pacifier use was associated with a significant reduced risk of SIDS (Summary OR: 0.71 [95% CI: 0.59�0.85]):

Pacifier use during last sleep (in cases) or reference sleep (in controls) showed a stronger and more consistent association with SIDS protection:

This meta-analysis is a basis for the American Academy of Pediatricians's new recommendations on SIDS protection, which encouraged pacifier use at nap time or bed time.

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